HILTON HEAD ISLAND, S.C. -- On a day that began with three players tied for the lead and a season-high 91 players having the made cut, only one was atop the leaderboard at the end of it.
Charley Hoffman birdied four of his first five holes Saturday and shot 66 to take a two-stroke lead through 54 holes at the RBC Heritage.
Webb Simpson is along in second after a 65, his career-low here, while Kevin Streelman is another stroke back after a 69 on Saturday.
Graeme McDowell and Brendon de Jonge share fourth at 7 under, while eight others, including Ryo Ishikawa, Camilo Villegas, Billy Horschel and Bill Haas, are tied at 6 under.
Jim Furyk, who won here in 2010, is another stroke back.
This marks the second year in a row that Hoffman has found himself in contention here.
A year ago, he shot 65 in the second round before eventually finishing eighth.
Early on in his career, however, he struggled with Harbour Town's tight fairways and small greens.
"I guess I wasn't mature enough to play this course," he said. "Once you learn what side of the fairway to leave it on and where to miss, you have a real big advantage."
Hoffman hit just eight greens on Saturday, but scrambled well and finished with just 21 putts on his way to five birdies and zero bogeys.
A win here Sunday would be the third of Hoffman's career and first since 2010 in Boston.